Sikeston was founded in 1860 at the end of the Cairo and Fulton Railroad, and this restored 1916 Missouri Pacific depot, on the National Register of Historic Places, is now the city’s museum and cultural center.
- Where
- 116 W. Malone Avenue, Sikeston, MO 63801
- Phone
- (573) 481-9967
Verify before relying on this. Hours, fees, access, and regulations change — check with the park, area, or venue directly before a trip. Something out of date? Let us know.




